CCRN Test 01: Core Body Systems & Critical Care

CCRN Test 01: Advanced Nursing Concepts

This exam reviews electrolyte balance, blood gas values, and heart pacing.

Acidosis Check: Metabolic acidosis occurs when the pH is below 7.35 and the bicarbonate is below 22.
Normal Ratios: A healthy BUN to creatinine ratio stays under 20:1. Higher numbers often mean dehydration.
Drug Safety: Mannitol is an osmotic diuretic. It is mostly used to lower brain swelling, not just for basic fluid loss.
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Q:1What is the correct order of the four layers of the gut wall from the outside (superficial) to the inside?
The Serosa is the outer covering. The Mucosa is the lining where food touches. The correct order is Serosa, Muscularis, Submucosa, and Mucosa.
Q:2Which drug type is used most often to treat agitation from delirium in the ICU?
1. Antipsychotics
2. Benzodiazepines
3. Antidepressants
Antipsychotics like haloperidol are the main choice. Benzodiazepines can often make delirium worse.
Q:3What is a normal BUN-to-creatinine ratio?
A ratio under 20:1 is normal. If the BUN rises much higher than the creatinine, the patient might be dehydrated.
Q:4Which of these is an osmotic diuretic?
1. Mannitol
2. Furosemide
3. Ethacrynic acid
Mannitol works by pulling water into the kidneys via osmosis. Furosemide is a loop diuretic.
Q:5Which two chemicals come from blood vessel linings to squeeze the vessel shut during an injury?
Endothelin and Thromboxane A2 are strong vasoconstrictors that help stop bleeding by narrowing the vessel.
Q:6Which condition comes from brain damage that affects movement and posture?
Cerebral palsy happens when the parts of the brain that control muscles are damaged during development.
Q:7Damage to the zona glomerulosa in the adrenal gland affects which hormone?
The zona glomerulosa is the outer layer of the adrenal cortex. It makes aldosterone to balance salt.
Q:8Which white blood cell releases histamine and heparin during inflammation?
Basophils are granulocytes. They carry histamine to open vessels and heparin to prevent early clots.
Q:9Which list shows the correct number of bones in the adult spine?
The spine has 7 cervical (neck), 12 thoracic (chest), and 5 lumbar (lower back) vertebrae. The sacrum and coccyx are fused.
Q:10Which isotonic fluid is best for a patient with low blood volume?
Normal Saline (0.9%) is isotonic. It stays in the blood vessels to help with blood pressure.
Q:11In the four phases of breathing, what happens during Phase III (Diffusion)?
Diffusion is the step where oxygen enters the blood and carbon dioxide leaves it in the lungs.
Q:12What happens in dipsogenic diabetes insipidus?
In this type of DI, the patient drinks so much that the brain stops sending out the hormone that holds in water.
Q:13How is a patient with tularemia (a bacterial disease) usually treated?
Tularemia is a bacterial infection. Doctors use antibiotics like gentamicin to kill the bacteria.
Q:14Which lab results show metabolic acidosis?
Acidosis means a low pH. Metabolic means the problem is with the bicarbonate (the base).
Q:15Which of these is NOT one of the four main acid-base problems?
The four main ones are Respiratory and Metabolic versions of Acidosis and Alkalosis. Renal tubular acidosis is just a specific type of metabolic acidosis.
Q:16What is the most common type of hole in the wall between the heart's upper chambers (ASD)?
Ostium secundum is the most common ASD. It happens near the center of the wall between the atria.
Q:17Which of these drugs open up blood vessels directly?
1. Nitroglycerin
2. Furosemide
3. Nitroprusside
Nitroglycerin and Nitroprusside act on the muscles of the vessels. Furosemide is for urine output.
Q:18In the Synergy Model, which of these is NOT considered a clinical outcome of care?
Clinical outcomes are facts like wellness or death. How the patient feels about it is a "characteristic," not an outcome.
Q:19The SA node uses two types of cells. What are they?
Pacemaker cells start the beat. Transitional cells help the signal travel into the rest of the heart.
Q:20Which organ does NOT help the GI tract digest food?
The spleen filters blood and helps the immune system. It does not help digest food.

Test 01 Key Study Points

1. GI Layers The gut has four layers. From the outside in, they are Serosa, Muscularis, Submucosa, and Mucosa.
2. Adrenal Cortex The Zona Glomerulosa makes Aldosterone. This hormone manages salt and water in the body.
3. SA Node Cells The heart's natural pacemaker uses P-cells to start the spark and T-cells to pass it along.
4. Isotonic Fluids 0.9% Normal Saline is the standard fluid for volume loss because it does not make cells shrink or swell.

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